Day Trip from Florence to Rome and visit at the Vatican Museums

Full-Day Tour from Florence to Rome and visit of the Vatican City

14 h
Day Trips & Excursions
difficulty Medium
Wheelchair Not Accessible
Skip the Line!Immediate confirmation

Visit of Rome, Vatican and Sistine Chapel from Florence by train

Discover the timeless heritage of Vatican city with our unique tour from Florence. Arrive in Rome and have a guided tour of the Vatican attractions, like the Vatican Museums with the Sistine Chapel, Saint Peter Basilica and more. Explore the rest of Rome at your own pleasure for the rest of the day

Day Trip from Florence to Rome and visit at the Vatican Museums highlights: 

  • Join this one-day tour from Florence to discover all the wonders of Rome
  • Discover the amazing artistic heritage of the Vatican Museums
  • Admire the fascinating masterpieces of Michelangelo, the Sistine Chapel and La Pietà
  • Join this inspiring tour and discover the famous Saint Peter Basilica
  • Enjoy your free time and your underground daily ticket to explore and admire the best attractions of Rome

There are certainly many things to see and know about the eternal city of Rome, with its thousands of monuments and attractions. Some would say that a lifetime is not enough to discover every corner and aspect of this destination, but we will try our best with our daily tour in Rome from Florence!

A day tour from Florence by train to visit Rome and its attractions

We offer you the opportunity to explore some of the most famous and fascinating attractions of the city with a unique tour of Rome from Florence. This tour will focus on the marvelous Vatican and its monuments, the interesting Vatican Museums, the stunning Sistine Chapel or the gorgeous St. Peter Basilica, but also other treasures of Vatican City.
The tour of Vatican from Florence will begin with a train ride from the charming Florence

Take a train to Rome and admire the Vatican Museums, the Sistine Chapel and St. Peter's Basilica

You will arrive in Rome by train in the morning. You will catch the train from Santa Novella Station in Florence, where you will be assisted from our staff. Once in Rome, you will get by your own to the Vatican City and you will meet with our local expert guide, ready to start your incredible tour. Your guide will take you to the Vatican Museums, for an unforgettable journey into the history of art. As one of the richest and most interesting museums in the world, you will have the opportunity to admire and learn more about some amazing painting and sculpture masterpieces, but also religious art.
The highlight of the Vatican Museums tour is the Sistine Chapel, where visitors have the unforgettable chance to admire the masterpiece of Michelangelo, especially the impressive Last Judgment paintings. The guide will also lead you to other areas of the museum to admire other famous artworks, like the Pio-Clementino halls for the Laocoon or the Apollo Belvedere, the Tapestries, the Maps Galleries and others.

Enjoy some free time in the afternoon to visit Rome as you prefer

The next stop in this inspiring tour of Vatican and Rome from Florence will be inside the Saint Peter Basilica, one of the most recognized religious edifice in the world. After admiring the exterior architecture, the guide will present the famous sculpture of Michelangelo, La Pietà. This is considered among the most beautiful sculptures in the world and for good reason. You will also have time to admire the other marvels of the basilica, including the Baldachin Altar by Bernini and others.
This magnificent experience in Vatican City will conclude with the Colonnade of St. Peter Square, but the tour can continue in Rome at your free will. You can explore the city with your one day metro pass and discover the other attractions of the city, like the Coliseum, the Pantheon, Fontana di Trevi, the Roman Forum and so many more.
After your day in Rome, you will take the train back to Florence.

Other tours to visit Rome, the eternal city, and the Vatican city state

If you are thinking of visiting Rome for more time than a single day, ItalyXP offers several other ways to explore the masterpieces of Roman historical center, like the Tour on Vintage Fiat 500, for those who want to experience Rome on board a car that is a symbol of Italy; moreover, if you want to visit the city of the Vatican, with a private tour in the Basilica of San Pietro and Vatican Museums, ItalyXP offers a complete tour of the beauties of the smallest state in the world.

  • Departure from Florence Santa Maria Novella
  • Vatican Museums
  • Departure from Rome 
  • Florence
  • Train tickets from/to Florence
  • Assistance at Santa Maria Novella station
  • 1 day Rome Subway ticket
  • Professional tour guide at the Vatican City
  • Skip-the-line ticket to Vatican Museums, Sistine Chapel and St. Peter's Basilica
  • Lunch
  • Tips (optional)
Meeting point: 

Meeting point information and local telephone numbers at your destination are included on your Confirmation Voucher.


Please note that this tour is not refundable.
The tour will be in the afternoon instead of morning during low season.
This tour is free for infants 0-2 years old (no seats reserved on the train). We regret to inform that this tour is not suitable for guests with impaired mobility.
No tour leader on the tour. Clients are requested to reach the meeting point in Rome on their own.
We recommend wearing appropriate clothing to access the places of worship, for both men and women: no shorts, miniskirts, tank tops or shirts that leave bare shoulders and knees. Compliance with these rules is mandatory for entering the Saint Peter's Basilica and the Vatican Museums. We cannot be held responsible for entry denied due to improper dress.
During particular events St Peter's Basilica will not be accessible; in these days you will be offered a longer stay inside the Museums instead.

Confirmation will be received at time of booking. You will receive a voucher. This is your ticket and proof of purchase.